The recommended dosage is 1 tablet 3-4 times daily, with a maximum of 4 tablets per day. Tablets should be taken with a sufficient amount of liquid at intervals of at least 4 hours.

Yes, it is contraindicated in patients with severe hepatic or renal impairment, alcoholism, blood disorders, Gilbert's syndrome, and those using MAOIs, tricyclic antidepressants, or beta-blockers.

The drug is not recommended during pregnancy due to increased risk of spontaneous abortion associated with caffeine. Use during breastfeeding is also not recommended as both components are excreted into breast milk.

Immediate medical attention is required. Treatment may include activated charcoal if taken within 1 hour, and N-acetylcysteine administration, which is most effective within 8 hours of ingestion.