# β-Lactam Injectables: Cephalosporins & Carbapenems

*Sterile β-lactam antibiotic powders (cephalosporins & carbapenems) for injection/infusion*

Sterile β-lactam antibiotics (cephalosporins and carbapenems) filled in a separate, dedicated Beta building to prevent cross-contamination. Fully upgraded and automated multi-filling-volume lines produce 15 million vials per year (≈20 tons of API, average 1.3 g per vial) across an 880 m² production area, under EU GMP.

## Overview

- **Manufacturer:** Anfarm Hellas S.A.
- **Product type:** Antibiotics
- **Usage classification:** Prescription-only (Rx) sterile injectable antibiotics for hospital use

## Key features

- Sterile powders for solution for injection/infusion in single-use vials
- Cephalosporins (Cefotaxime, Ceftaroline, Ceftriaxone, Cefuroxime) and carbapenems (Ertapenem, Imipenem+Cilastatin, Meropenem)
- Multi-filling-volume automated filling lines
- Produced in a segregated β-lactam facility per GMP containment requirements

## Highlights & advantages

### Competitive Advantage

- Segregated, dedicated β-lactam (Beta) building: no cross-contamination with non-β-lactam lines
- 15 million vials/year capacity (~20 tons API) with multi-filling-volume automation
- Both cephalosporin and carbapenem chemistries under one EU-GMP roof
- Available for out-licensing and contract manufacturing

### Regulatory Certification

- EU GMP Manufacturing License (EOF / Greek Health Authorities)

### Clinical Indication

- Serious Gram-positive and Gram-negative bacterial infections
- Hospital and intensive-care infections requiring broad-spectrum β-lactam antibiotics

### Packaging Logistics

- Sterile powder in single-dose vials (IM/IV)
- Average filling volume ~1.3 g per vial

## Specifications

| Specification | Value |
| --- | --- |
| Dosage form | Sterile powder for solution for injection/infusion (β-lactam) |
| Production capacity | 15 million vials per year (~20 tons API) vials/year |
| Average filling volume | 1.3 g/vial |
| Production area | 880 m² |
| Facility | Dedicated segregated Beta building |

## Variants

- **Cefotaxime** (Strength: 1 g/vial (IM, IV); Sub-class: Cephalosporin; Dosage form: Ps.Inj.Sol (powder for solution for injection)): 3rd-generation cephalosporin
- **Ceftaroline Fosamil** (Strength: 600 mg/vial; Sub-class: Cephalosporin; Dosage form: Pd.C.So.Inf): 5th-generation (anti-MRSA) cephalosporin
- **Ceftriaxone** (Strength: 1 g/vial (IM, IV); Sub-class: Cephalosporin; Dosage form: Ps.Inj.Sol): 3rd-generation cephalosporin
- **Cefuroxime** (Strength: 750 mg & 1.5 g/vial; 250 mg & 500 mg tablet; Sub-class: Cephalosporin; Dosage form: Pd.Inj.Sol (injectable) / F.C.Tab (oral)): 2nd-generation cephalosporin (injectable + oral film-coated tablet)
- **Ertapenem** (Strength: 1 g/vial; Sub-class: Carbapenem; Dosage form: Pd.C.So.In): Carbapenem antibiotic
- **Imipenem + Cilastatin** (Strength: (500 + 500) mg/vial; Sub-class: Carbapenem; Dosage form: Pd.Sol.Inf): Carbapenem + renal dehydropeptidase inhibitor
- **Meropenem** (Strength: 500 mg, 1 g & 2 g/vial; Sub-class: Carbapenem; Dosage form: Pd.I.S.Inf): Broad-spectrum carbapenem

## Frequently asked questions

### Why is the β-lactam line separate?

β-lactam antibiotics require containment segregation to prevent cross-contamination. Anfarm fills them in a dedicated Beta building with its own lines producing 15 million vials/year.

### What is the β-lactam production capacity?

Approximately 15 million vials per year (~20 tons of API, average 1.3 g per vial) across an 880 m² dedicated area.

## Documents

- [ANFARM Company Presentation](https://api.dev.mytradeloop.com/storage/10900~YRpe0P9pFAG1Cw3-) (company_profile, en, 30p)
- [ANFARM Product List Flyer](https://api.dev.mytradeloop.com/storage/10902~hTiHhVEVOvxQ5ILL) (brochure, en, 2p)
- [ANFARM International Product List](https://api.dev.mytradeloop.com/storage/10904~WVrEwtxrVWikYVkM) (catalog, en)

## Browse placement

- Pharmaceuticals & Biologics › Anti-infectives

## Tags

15m-vials-year, dedicated-beta-building, 20-t-api, beta lactam antibiotics, cephalosporin injection, carbapenem injection, ceftriaxone vial, meropenem vial, ertapenem vial, sterile antibiotic powder, generic antibiotics manufacturer

> Made by [Anfarm Hellas S.A.](https://dev.mytradeloop.com/en/companies/anfarm-hellas-s-a-9684). Contact the manufacturer via their profile page.

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