No. Ceftriaxone is incompatible with calcium-containing solutions (e.g., Ringer's or Hartmann's solution) due to the risk of ceftriaxone-calcium precipitate formation.

The prepared solution is stable for 24 hours when stored at 2-8 °C or for 6 hours when stored at room temperature.

No dosage reduction is needed for patients with impaired renal function provided liver function is intact, except in cases of pre-terminal renal failure (creatinine clearance <10 mL/min) where the daily dose should not exceed 2g.